Our study is the first to apply rearing by a wet nurse in the preterm rabbit pup IVH model instead of gavage feeding.
We also cannot exclude that with increasing age neurobehavioral injury may manifest and longer-term follow-up is also warranted.
The risk factors for IVH include immaturity gestational age, birth weight , vascular fluctuations hypotension, need for resuscitation , and inflammation interleukin 1B polymorphism, and chorioamnionitis.
Sections were then exposed for 20 min to a 0.
The motor examination included muscle tone and strength, gait, and righting reflex.
The importance of breastfeeding in rabbit pups was emphasized in a recent study, where term pups reared by does display improved social interactions when compared to term-born gavage reared pups.
For the first time, we report the long-term effects of IVH leading to PHVD in a preterm animal model that include alterations to myelination, including organizational changes, decreased mature neuron and presynaptic terminal densities, altered cortical organization, and altered PV-positive interneurons number and maturation.
Recent data from Dohare et al.